Sustained Viral Resilience
Backed by £46m, this programme sits within the Sculpting Innate Immunity opportunity space and seeks to create a new class of medicines that provide durable, broad-spectrum protection against respiratory viruses by engineering the innate immune system.
Funding – now closed
We’re looking to fund a diversity of approaches in order to foster a vibrant research community and maximise collective progress toward the programmatic goals. We intend to fund approaches to engineering the innate immune system to create what we’re calling sustained innate immunoprophylactics (SIIPs), as well as activities that develop methods to accelerate adoption of SIIP candidates, and research that facilitates future translation and commercialisation of SIIPs.
We’re primarily seeking applications from those whose work involves newer approaches or radical — as opposed to incremental — advances from existing approaches. We don’t require preliminary data, but encourage you to provide in detail your reasoned basis for expected success.
Technical areas
We’ll fund ambitious projects across the following Technical Areas (TAs):
TA1 | Explorers: Focused on providing proof-of-concept evidence that sustained innate immunoprophylactics (SIIPs) are possible by designing, building and testing candidates in in vitro and in vivo models.
TA2 | Accelerators: Focused on developing tools, platforms, models, standards, or datasets in order to accelerate the process of bringing new SIIP candidates to strong proof-of-concept.
TA3 | Translators: Focused on conducting research that facilitates the clinical translation and future commercialisation of SIIPs, ultimately smoothing the pathway from technical proof-of-concept to real-world impact.
Learn more about funding for this programme in the resources below.
Resources
Clarification questions
If you have any questions, please use the chat function on this page for the quickest response – you'll find the icon in the bottom right-hand corner of your screen. It can guide you to the right information or connect you with the ARIA team if needed. We’ll update this page regularly with questions and answers.
Nb: Clarification questions that need to be reviewed by the ARIA team should be submitted via the chat function no later than 4 days prior to the relevant deadline date. Clarification questions received after this date will not be reviewed.
The following question(s) (included here in a generalised form) have been received and we are publishing the answer(s) as they may contain information that is relevant to other applicants.